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To clean suede clothing, if ordinary brushing doesn't do the trick, try rubbing the spot lightly with an an artist's eraser or an emery board, then steam over a boiling kettle. A stain on suede that won't brush or wipe off should be treated by a professional suede cleaner as quickly as possible. Though you can try cleaning it yourself with a suede-cleaning product, you may end up doing more harm than good. You can protect suede by spraying it with a silicone spray that you can purchase at most shoe stores.